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FineTest

SKU(재고 관리 코드):FNab03225

anti- FRS2 antibody

anti- FRS2 antibody

size

Dive into the world of signal transduction and cell growth research with our Anti-FRS2 Antibody, available in a 100µg vial. Fibroblast Growth Factor Receptor Substrate 2 (FRS2) plays a pivotal role in mediating signaling cascades, impacting cell proliferation, differentiation, and survival. This highly specific antibody empowers researchers to explore FRS2's functions, contributing to a deeper understanding of cellular signaling pathways and disease mechanisms.

Key Features:

  • Exceptional Specificity: Our Anti-FRS2 Antibody is rigorously validated to target FRS2 specifically, ensuring minimal cross-reactivity.
  • Versatile Applications: Ideal for a wide range of experimental techniques, including Western blotting, immunohistochemistry, and co-immunoprecipitation.
  • Sufficient Quantity: With 100µg of antibody, you have ample supply for multiple experiments.
  • High-Quality Standards: Manufactured to meet stringent industry standards, assuring consistent and reproducible results.
  • Advance Your Research: Whether you're focused on cell signaling, growth factor pathways, or cellular responses, our Anti-FRS2 Antibody offers precision and reliability.

Product Name

FRS2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

IMMUNOGEN INFORMATION

Immunogen

fibroblast growth factor receptor substrate 2

Synonyms

FGFR signaling adaptor SNT, FGFR substrate 2, FRS2, FRS2A, FRS2alpha, SNT, SNT 1, SNT1

Observed MW

60 kDa

APPLICATION

Tested Application

ELISA, IHC, WB, IF

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

Q8WU20

IMAGES

 

Immunohistochemistry of paraffin-embedded human prostate cancer using FNab03225(FRS2 antibody) at dilution of 1:50
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab03225(FRS2 Antibody) at dilution of 1:1000

 

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