anti- FXN antibody

Dive into the world of mitochondrial biology and its implications for cellular health with our Anti-FXN Antibody, available in a 100µg format. Frataxin (FXN) is a crucial protein involved in mitochondrial function, and its study has direct relevance to mitochondrial disorders and broader cellular biology. This highly specific antibody empowers researchers to investigate FXN's functions, contributing to a deeper understanding of mitochondrial health and disease mechanisms.

Key Features:

• Exceptional Specificity: Our Anti-FXN Antibody is rigorously validated to specifically target FXN, minimizing the risk of cross-reactivity.
• Versatile Applications: Ideal for a variety of experimental techniques, including Western blotting, immunofluorescence, and studies related to mitochondrial disorders, neurodegenerative diseases, and energy metabolism.
• Adequate Quantity: With 100µg, you have sufficient antibody for multiple experiments.
• High-Quality Standards: Manufactured to meet the highest industry standards, ensuring consistent and reproducible results.
• Elevate Your Research: Whether you're focused on mitochondrial biology, neurodegeneration, or FXN's functions, our Anti-FXN Antibody offers precision and reliability.

Product Name

FXN antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

FXN, also named as FRDA, X25, m81-FXN, d-FXN, m78-FXN and i-FXN, belongs to the frataxin family. It promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. FXN may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. FXN is cleaved to be 4 chains. The mature form of FXN is 14 or 18kDa.

IMMUNOGEN INFORMATION

Immunogen

frataxin

Synonyms

CyaY, d FXN, FA, FARR, frataxin, Frataxin(81 210), Frataxin, mitochondrial, FRDA, Friedreich ataxia protein, FXN, i FXN Frataxin(56 210), m56 FXN Frataxin(78 210), m78 FXN Frataxin mature form, m81 FXN, X25

Observed MW

14 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q16595

IMAGES