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SKU(재고 관리 코드):FNab03346

anti- GAR1 antibody

anti- GAR1 antibody

size

Delve into the mysteries of ribosome biogenesis and RNA processing with our Anti-GAR1 Antibody. This indispensable research tool empowers you to investigate GAR1-related studies. Key features include:

  • High Specificity: Each 100µg vial contains antibodies meticulously designed to specifically target GAR1, ensuring accuracy and reliability in your experiments.
  • Enhanced Sensitivity: This antibody is highly sensitive, allowing for the precise detection of GAR1 in various experimental setups.
  • Versatile Applications: Suitable for Western blotting, RNA immunoprecipitation, and immunohistochemistry, this antibody accommodates diverse research methodologies.
  • Biogenesis Insights: Gain valuable insights into GAR1's role in ribosome assembly, its significance in RNA modification, and its implications in various cellular processes and diseases.

Empower your studies in molecular biology and RNA processing with our Anti-GAR1 Antibody, your key to unraveling the complexities of ribosome biogenesis and RNA modification.

Product Name

GAR1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein(H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase(TERT) holoenzyme.

IMMUNOGEN INFORMATION

Immunogen

GAR1 ribonucleoprotein homolog(yeast)

Synonyms

NOLA1

Observed MW

28kd

APPLICATION

Tested Application

ELISA, WB, IHC, IP, IF

Recommended Dilution

WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

Q9NY12

IMAGES

 

Immunohistochemistry of paraffin-embedded human skin cancer using FNab03346(GAR1 antibody) at dilution of 1:50
IP Result of anti-GAR1 (IP: FNab03346, 3ug; Detection: FNab03346 1:500) with A375 cells lysate 3000ug.
A375 cells were subjected to SDS PAGE followed by western blot with FNab03346(GAR1 antibody) at dilution of 1:500

 

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