anti- GEMIN8 antibody

Shed light on Gem-associated Protein 8 (GEMIN8) and its role in RNA processing and cellular functions with our Anti-GEMIN8 Antibody. This meticulously crafted research tool is designed to assist you in your investigations related to GEMIN8 with precision and accuracy. Key features include:

• High Specificity: Our antibody is specifically tailored to target GEMIN8, ensuring accurate and reliable results in your experiments. It recognizes GEMIN8 with exceptional specificity, allowing for confident data interpretation.

• RNA Processing Insights: Gain valuable insights into GEMIN8's role in small nuclear ribonucleoprotein assembly (snRNP), its potential implications in mRNA splicing, and its significance in cellular RNA processing.

• Versatile Sizing: The 100µg size is ideal for multiple experiments while ensuring product freshness and quality.

• Wide Applications: This antibody is suitable for various research applications, from studying RNA-related processes to exploring GEMIN8's interaction with other RNA-binding proteins.

Advance your research in the fields of RNA biology, cellular functions, and mRNA splicing, revealing the intricate functions of GEMIN8 in RNA processing.

Product Name

GEMIN8 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.

IMMUNOGEN INFORMATION

Immunogen

gem(nuclear organelle) associated protein 8

Synonyms

FAM51A1

Observed MW

32 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9NWZ8

IMAGES