anti- GNAI2 antibody

anti- GNAI2 antibody

Product Name

GNAI2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Guanine nucleotide-binding proteins(G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. Isoform sGi2: Regulates the cell surface density of dopamine receptors DRD2 by sequestrating them as an intracellular pool.

IMMUNOGEN INFORMATION

Immunogen

guanine nucleotide binding protein(G protein), alpha inhibiting activity polypeptide 2

Synonyms

GNAI2B, GIP, H_LUCA15.1, H_LUCA16.1

Observed MW

35-40 kDa

APPLICATION

Tested Application

ELISA, WB, IF, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

P04899

IMAGES

Immunohistochemistry of paraffin-embedded rat kidney tissue slide using FNab03532(GNAI2 Antibody) at dilution of 1:50

Immunofluorescent analysis of Hela cells, using FNab03532(GNAI2 Antibody) at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG.

IP Result of anti-GNAI2 (IP: FNab03532, 4ug; Detection: FNab03532 1:1000) with mouse kidney tissue lysate 3000ug.

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab03532(GNAI2 antibody) at dilution of 1:1000