anti- GNB5 antibody

anti- GNB5 antibody

Product Name

GNB5 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Heterotrimeric guanine nucleotide-binding proteins(G proteins) function as transducers downstream of G protein-coupled receptors(GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

IMMUNOGEN INFORMATION

Immunogen

guanine nucleotide binding protein(G protein), beta 5

Observed MW

39-42 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O14775

IMAGES

Immunohistochemistry of paraffin-embedded human ovary tumor using FNab03543(GNB5 antibody) at dilution of 1:100

IP Result of anti-GNB5 (IP:FNab03543, 4ug; Detection:FNab03543 1:500) with rat brain tissue lysate 4000ug.

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab03543(GNB5 antibody) at dilution of 1:1000