anti- GTF2IRD1 antibody

anti- GTF2IRD1 antibody

Product Name

GTF2IRD1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer(USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8(By similarity).

IMMUNOGEN INFORMATION

Immunogen

GTF2I repeat domain containing 1

Synonyms

CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12

Observed MW

145 kDa, 120 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9UHL9

IMAGES

Immunohistochemistry of paraffin-embedded human heart using FNab03716(GTF2IRD1 antibody) at dilution of 1:100

HeLa cells were subjected to SDS PAGE followed by western blot with FNab03716(GTF2IRD1 antibody) at dilution of 1:500