anti- HMGCL antibody

anti- HMGCL antibody

Product Name

HMGCL antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase

Synonyms

HL

Observed MW

30 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P35914

IMAGES

Immunohistochemistry of paraffin-embedded human kidney using FNab03928(HMGCL antibody) at dilution of 1:100

mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab03928(HMGCL antibody) at dilution of 1:1000