anti- HSP90AB1 antibody

anti- HSP90AB1 antibody

Product Name

HSP90AB1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

IMMUNOGEN INFORMATION

Immunogen

heat shock protein 90kDa alpha(cytosolic), class B member 1

Synonyms

HSP90B, HSPC2, HSPCB

Observed MW

83-90kd

APPLICATION

Tested Application

ELISA, WB, IHC, IF, FC, IP

Recommended Dilution

WB: 1:2000-1:10000; IP: 1:500-1:1000; IHC: 1:250-1:1000; IF: 1:10-1:100

UNIPROT INFORMATION

UniProt ID

P08238

IMAGES

Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab04053(HSP90AB1 antibody) at dilution of 1:50

Immunofluorescent analysis of HepG2 cells, using FNab04053(HSP90AB1 antibody) at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

IP Result of anti-HSP90AB1 (IP: FNab04053, 4ug; Detection: FNab04053 1:700) with NIH/3T3 cells lysate 1200ug.

HeLa cells were subjected to SDS PAGE followed by western blot with FNab04053(HSP90AB1 antibody) at dilution of 1:1000