anti- KLHL21 antibody

anti- KLHL21 antibody

Product Name

KLHL21 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex(CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

IMMUNOGEN INFORMATION

Immunogen

kelch-like 21(Drosophila)

Synonyms

KIAA0469

Observed MW

67kd

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9UJP4

IMAGES

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab04619(KLHL21 Antibody) at dilution of 1:50

IP Result of anti-KLHL21 (IP:FNab04619, 3ug; Detection:FNab04619 1:300) with HeLa cells lysate 1800ug.

A431 cells were subjected to SDS PAGE followed by western blot with FNab04619(KLHL21 antibody) at dilution of 1:400