anti- L2HGDH antibody

anti- L2HGDH antibody

Product Name

L2HGDH antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.

IMMUNOGEN INFORMATION

Immunogen

L-2-hydroxyglutarate dehydrogenase

Synonyms

C14orf160

Observed MW

40 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9H9P8

IMAGES

Immunohistochemistry of paraffin-embedded human stomach using FNab04670( L2HGDH Antibody) at dilution of 1:100 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

mouse small intestine tissue were subjected to SDS PAGE followed by western blot with FNab04670(L2HGDH antibody) at dilution of 1:1000