anti- MADCAM1 antibody

anti- MADCAM1 antibody

Product Name

MADCAM1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.

IMMUNOGEN INFORMATION

Immunogen

mucosal vascular addressin cell adhesion molecule 1

Observed MW

40 kDa

APPLICATION

Tested Application

ELISA, IHC

Recommended Dilution

IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q13477

IMAGES

Immunohistochemistry of paraffin-embedded human small intestine tissue slide using FNab04927(MAdCAM1 antibody) at dilution of 1:400