anti- MAGEA6 antibody

anti- MAGEA6 antibody

Product Name

MAGEA6 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.

IMMUNOGEN INFORMATION

Immunogen

melanoma antigen family A, 6

Synonyms

MAGE6

Observed MW

66-70 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P43360

IMAGES

Immunohistochemistry of paraffin-embedded human lung cancer using FNab04939(MAGEA6 antibody) at dilution of 1:50

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab04939(MAGEA6 antibody) at dilution of 1:500