anti- MME,CD10 antibody

anti- MME,CD10 antibody

Product Name

MME,CD10 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

MME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas(PMID:15286660).This antibody is specific to MME.

IMMUNOGEN INFORMATION

Immunogen

membrane metallo-endopeptidase

Synonyms

Atriopeptidase, CALLA, CD10, DKFZp686O16152, Enkephalinase, EPN, membrane metallo endopeptidase, MME, NEP, Neprilysin, Neutral endopeptidase, Neutral endopeptidase 24.11

Observed MW

90-110 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P08473

IMAGES

Immunohistochemistry of paraffin-embedded human renal cell carcinoma using FNab05232(MME,CD10 antibody) at dilution of 1:100

pig kidney tissue were subjected to SDS PAGE followed by western blot with FNab05232(MME,CD10 Antibody) at dilution of 1:1000