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FineTest

SKU(재고 관리 코드):FNab05236

anti- MMP14 antibody

anti- MMP14 antibody

size

anti- MMP14 antibody

Product Name

MMP14 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

IMMUNOGEN INFORMATION

Immunogen

matrix metallopeptidase 14 (membrane-inserted)

Synonyms

MMP-14

Observed MW

65 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P50281

IMAGES

Immunohistochemistry of paraffin-embedded human liver cancer using FNab05236(MMP14 Antibody) at dilution of 1:100

mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab05236(MMP14 antibody) at dilution of 1:1000

RELATED PRODUCTS

STATEMENT

Manuals on the web are for your reference only, specifications are subject to the delivery manuals.

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