anti- MRPL12 antibody

anti- MRPL12 antibody

Product Name

MRPL12 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex.

IMMUNOGEN INFORMATION

Immunogen

mitochondrial ribosomal protein L12

Synonyms

RPML12

Observed MW

21 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P52815

IMAGES

Immunohistochemistry of paraffin-embedded human esophageal smooth muscle using FNab05315(MRPL12 antibody) at dilution of 1:100

HeLa cells were subjected to SDS PAGE followed by western blot with FNab05315(MRPL12 antibody) at dilution of 1:1000

RELATED PRODUCTS

• Recombinant Human MRPL12

STATEMENT

Manuals on the web are for your reference only, specifications are subject to the delivery manuals.

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