anti- NANOS3 antibody

anti- NANOS3 antibody

Product Name

NANOS3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and-independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells(PGCs) from apoptosis.

IMMUNOGEN INFORMATION

Immunogen

nanos homolog 3(Drosophila)

Synonyms

Nanos homolog 3, nanos homolog 3 (Drosophila), NANOS1L, NANOS3, NOS 3, NOS3

Observed MW

26-30 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:200-1:1000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P60323

IMAGES

Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab05542(NANOS3 Antibody) at dilution of 1:200

mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab05542(NANOS3 antibody) at dilution of 1:300