anti- NXF1 antibody

PRODUCT INFORMATION

Product Name

NXF1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements(CTE) and in the export of mRNA from the nucleus to the cytoplasm(TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export.

IMMUNOGEN INFORMATION

Immunogen

nuclear RNA export factor 1

Synonyms

MEX67, mRNA export factor TAP, nuclear RNA export factor 1, NXF1, TAP, Tip associated protein, Tip associating protein

Observed MW

66-70 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB : 1:500-1:1000; IHC : 1:20-1:200; IF : 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9UBU9

Hela cells were subjected to SDS PAGE followed by western blot with FNab05941( NXF1 Antibody) at dilution of 1:600