anti- PDE3B antibody

PRODUCT INFORMATION

Product Name

PDE3B antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

IMMUNOGEN INFORMATION

Immunogen

phosphodiesterase 3B, cGMP-inhibited

Synonyms

CGI PDE B, CGIP1, cGIPDE1, HcGIP1, PDE3B

Observed MW

124 kDa

APPLICATION

Tested Application

ELISA, IP

Recommended Dilution

IP: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

Q13370