anti- RBPMS antibody

anti- RBPMS antibody

Product Name

RBPMS antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins(PubMed:26347403). Binds to poly(A) RNA(PubMed:17099224, PubMed:26347403).

IMMUNOGEN INFORMATION

Immunogen

RNA binding protein with multiple splicing

Synonyms

HERMES

Observed MW

28-30 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF, FC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q93062

IMAGES

Immunohistochemistry of paraffin-embedded human ovary tumor using FNab07198(RBPMS antibody) at dilution of 1:50

mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab07198(RBPMS antibody) at dilution of 1:400