anti- RNF40 antibody

anti- RNF40 antibody

Product Name

RNF40 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

ring finger protein 40

Synonyms

BRE1B, KIAA0661

Observed MW

140 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF,IP

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:100; ChIP : 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

O75150

IMAGES

Immunohistochemistry of paraffin-embedded human testis using FNab07358(RNF40 antibody) at dilution of 1:50

Immunofluorescence analysis of MCF-7 cells using FNab07358( RNF40 Antibody) at dilution of 1:50

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab07358(RNF40 antibody) at dilution of 1:1000