anti- SEC14L1 antibody

anti- SEC14L1 antibody

Product Name

SEC14L1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

May play a role in innate immunity by inhibiting the antiviral RIG-I signaling pathway. In this pathway, functions as a negative regulator of DDX58/RIG-I, the cytoplasmic sensor of viral nucleic acids. Prevents the interaction of DDX58 with MAVS/IPS1, an important step in signal propagation(PubMed:23843640). May also regulate the SLC18A3 and SLC5A7 cholinergic transporters(PubMed:17092608).

IMMUNOGEN INFORMATION

Immunogen

SEC14-like 1

Synonyms

SEC14L

Observed MW

81 kDa, 77 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q92503

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