anti- SIAH1 antibody

anti- SIAH1 antibody

Product Name

SIAH1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

IMMUNOGEN INFORMATION

Immunogen

seven in absentia homolog 1 (Drosophila)

Synonyms

HUMSIAH

Observed MW

31 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q8IUQ4

IMAGES

Immunohistochemistry of paraffin-embedded rat brain using FNab07857(SIAH1 antibody) at dilution of 1:100

HeLa cells were subjected to SDS PAGE followed by western blot with FNab07857(SIAH1 antibody) at dilution of 1:1000