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AntibodySystem
SKU(재고 관리 코드):DHD37502
Research Grade Lintuzumab
Research Grade Lintuzumab
Catalog No.: DHD37502
| Catalog No. | DHD37502 |
|---|---|
| Product name | Research Grade Lintuzumab |
| Size | 100 μg |
| Species reactivity | Human |
| Host species | Humanized |
| Isotype | IgG1-kappa |
| Applications | Research Grade Biosimilar |
| Description | Lintuzumab is a humanized monoclonal antibody, HuM195, that targets the cell surface antigen CD33 that is expressed on the vast majority of acute myeloid leukemia (AML) cells. [225 Ac]Ac-lintuzumab clinical trials were discussed in detail in reference . Lintuzumab is under investigation in clinical trial NCT00016159 (Chemotherapy Plus Monoclonal Antibody in Treating Patients With Acute Promyelocytic Leukemia). |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. |
| Purity | >95% as determined by SDS-PAGE. |
| Clonality | Monoclonal |
| Target | Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, Siglec-3, CD33, gp67, SIGLEC3 |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin level | Please contact with the lab for this information. |
| Accession | P20138 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Alternative Names | 225Ac-lintuzumab, HuM195, SGN-33, SMART M195, HuM195, CAS: 166089-32-3 |
| Clone ID | Lintuzumab |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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