• Recombinant Human CD142/F3/TF Protein, C-His
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AntibodySystem

EHD00601

Recombinant Human CD142/F3/TF Protein, C-His

Recombinant Human CD142/F3/TF Protein, C-His

Catalog No.: EHD00601

Tissue factor, also called platelet tissue factor, factor III, or CD142, is a protein encoded by the F3 gene, present in subendothelial tissue and leukocytes. CD142, also known as ,Coagulation Factor III, and Thromboplastin, is a 45 kD type I transmembrane glycoprotein. CD142 is a high-affinity receptor for coagulation factor VII and initiates the extrinsic pathway of blood coagulation. CD142 also plays an important role in a variety of diseases such as sepsis, atherosclerosis, and cancer. It is expressed on the surface of a variety of cells that are physically separated from the circulating blood which include smooth muscle cells, fibroblasts, keratinocytes, glomerular epithelial cells (cytoplasmic inclusions), astrocytes, myocardium, liver stromal cells, pancreas cells, and is also expressed on activated monocytes and stimulated endothelial cells.

Catalog No. EHD00601
Product name Recombinant Human CD142/F3/TF Protein, C-His
Size 100 μg
Expression system Mammalian Cells
Protein length Met1-Glu251
Predicted molecular weight 29.24 kDa
Accession P13726
Description Tissue factor, also called platelet tissue factor, factor III, or CD142, is a protein encoded by the F3 gene, present in subendothelial tissue and leukocytes. CD142, also known as ,Coagulation Factor III, and Thromboplastin, is a 45 kD type I transmembrane glycoprotein. CD142 is a high-affinity receptor for coagulation factor VII and initiates the extrinsic pathway of blood coagulation. CD142 also plays an important role in a variety of diseases such as sepsis, atherosclerosis, and cancer. It is expressed on the surface of a variety of cells that are physically separated from the circulating blood which include smooth muscle cells, fibroblasts, keratinocytes, glomerular epithelial cells (cytoplasmic inclusions), astrocytes, myocardium, liver stromal cells, pancreas cells, and is also expressed on activated monocytes and stimulated endothelial cells.
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Purity >90% as determined by SDS-PAGE.
Applications ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level Please contact with the lab for this information.
Nature Recombinant
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Reconstitution Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Alternative Names Tissue factor, CD142, F3, Thromboplastin, Coagulation factor III, TF
Species Homo sapiens (Human)
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Note For research use only.
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