1
/
의
1
AntibodySystem
SKU(재고 관리 코드):KDB86901
Depatuxizumab ELISA Kit
Depatuxizumab ELISA Kit
Catalog No.: KDB86901
| Catalog No. | KDB86901 |
|---|---|
| Product name | Depatuxizumab ELISA Kit |
| Size | 96 T |
| Description | PRINCIPLE OF THE ASSAY This assay employs the quantitative competitive enzyme immunoassay technique. Recombinant Human EGFR has been pre-coated onto a microplate. Standards or samples are premixed with biotin-labeled antibody and then pipetted into the wells. Depatuxizumab in the sample competitively binds to the pre-coated protein with biotin-labeled Depatuxizumab. After washing away any unbound substances, Streptavidin-HRP is added to the wells. Following a wash to remove any unbound enzyme reagent, a substrate solution is added to the wells and color develops in inversely proportion to the amount of Depatuxizumab bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Applications | Used for the quantitative determination of Depatuxizumab concentration in serum and plasma. |
| Stability and Storage | The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition. |
| Detection method | Colorimetric |
| Precision | CV<20% |
| Sample type | Plasma, Serum |
| Assay type | Quantitative |
| Sensitivity | 79.88 ng/mL |
| Range | 156.25 - 10,000 ng/mL |
| Recovery | 80-120% |
| Background | Depatuxizumab Mafodotin (Depatux-M; ABT-414) is an antibody-drug conjugate consisting of a specific antibody against activated EGFR and a cytotoxic agent with antimicrotubule activity. The INTELLANCE 2/EORTC 1410 phase 2 trial produced interesting results for the combination regimen of Depatux-M and temozolomide in EGFR-amplified glioblastoma patients at first recurrence. For the first time worldwide, our work investigated the clinical outcome and safety of this combination in a real-life population. |
| Alternative Names | ABT-806, ABT-414, unconjugate: ABT-806, CAS: 1471999-69-5 |
| Shipping | 2-8 ℃ |
| Note | For Research Use Only. |
Share
