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SKU(재고 관리 코드):KDC25202
Emactuzumab ELISA Kit
Emactuzumab ELISA Kit
Catalog No.: KDC25202
| Catalog No. | KDC25202 |
|---|---|
| Product name | Emactuzumab ELISA Kit |
| Size | 96 T |
| Description | PRINCIPLE OF THE ASSAY This assay employs the quantitative competitive enzyme immunoassay technique. Recombinant Human CD115 has been pre-coated onto a microplate. Standards or samples are premixed with biotin-labeled antibody and then pipetted into the wells. Emactuzumab in the sample competitively binds to the pre-coated protein with biotin-labeled Emactuzumab. After washing away any unbound substances, Streptavidin-HRP is added to the wells. Following a wash to remove any unbound enzyme reagent, a substrate solution is added to the wells and color develops in inversely proportion to the amount of Emactuzumab bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Applications | Used for the quantitative determination of Emactuzumab concentration in serum and plasma. |
| Stability and Storage | When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. |
| Detection method | Colorimetric |
| Precision | CV<20% |
| Sample type | Plasma, Serum |
| Assay type | Quantitative |
| Sensitivity | 35.75 ng/mL |
| Range | 234.38 - 15,000 ng/mL |
| Recovery | 80-120% |
| Background | Emactuzumab, also known as RG-7155, is a humanized monoclonal antibody developed by Genentech/Roche. It was designed to directly against the tyrosine kinase receptor colony stimulating factor 1 receptor (CSF1R), which is also known as macrophage colony-stimulating factor receptor (M-CSFR) and Cluster of Differentiation 115 (CD115). Emactuzumab has been investigated in the treatment for the diseases including fallopian tube cancer, ovarian cancer, peritoneal cancer and solid tumors. The trail that emactuzumab combination regimen with selicrelumab (RG7876) in solid tumors is currently in Phase II. |
| Alternative Names | RG 7155, RO5509554, CAS: 1448221-67-7 |
| Shipping | 2-8 ℃ |
| Note | For Research Use Only. |
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