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SKU(재고 관리 코드):KDD49201
Zampilimab ELISA Kit
Zampilimab ELISA Kit
Catalog No.: KDD49201
| Catalog No. | KDD49201 |
|---|---|
| Product name | Zampilimab ELISA Kit |
| Size | 96 T |
| Description | PRINCIPLE OF THE ASSAY This assay employs the quantitative indirect enzyme immunoassay technique. Recombinant Human TGM2 has been pre-coated onto a microplate. Standards or samples are pipetted into the wells and any Zampilimab present is bound by the immobilized protein. After washing away any unbound substances, a biotin-labeled Mouse Anti-Human IgG antibody is added to the wells. After washing away any unbound substances, Streptavidin-HRP is added to the wells. Following a wash to remove any unbound enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of Zampilimab bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Applications | Used for the quantitative determination of Zampilimab concentration in serum and plasma. |
| Stability and Storage | When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. |
| Detection method | Colorimetric |
| Precision | CV<15% |
| Sample type | Plasma, Serum |
| Assay type | Quantitative |
| Sensitivity | 2.16 ng/mL |
| Range | 3.13 - 200 ng/mL |
| Recovery | 80-120% |
| Background | Zampilimab is an anti-transglutaminase 2 monoclonal antibody intended for the treatment of fibrosis such as Idiopathic Pulmonary Fibrosis (IDF) and Chronic Kidney Disease (CAI). Transglutaminase 2 is a multi-functional enzyme that modifies proteins by catalyzing the formation of intermolecular isopeptide bonds between glutamine and lysine side-chains. It plays a role in several biological functions and is associated in the pathology of several diseases.3 |
| Alternative Names | UCB-7858, UCB7858, CAS: 2098280-42-1 |
| Shipping | 2-8 ℃ |
| Note | For Research Use Only. |
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