• Cusatuzumab ELISA Kit
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AntibodySystem

KDE01901

Cusatuzumab ELISA Kit

Cusatuzumab ELISA Kit

Title

Catalog No.: KDE01901

Catalog No. KDE01901
Product name Cusatuzumab ELISA Kit
Size 96 T
Description PRINCIPLE OF THE ASSAY This assay employs the quantitative competitive enzyme immunoassay technique. Recombinant Human CD70 has been pre-coated onto a microplate. Standards or samples are premixed with biotin-labeled antibody and then pipetted into the wells. Cusatuzumab in the sample competitively binds to the pre-coated protein with biotin-labeled Cusatuzumab. After washing away any unbound substances, Streptavidin-HRP is added to the wells. Following a wash to remove any unbound enzyme reagent, a substrate solution is added to the wells and color develops in inversely proportion to the amount of Cusatuzumab bound in the initial step. The color development is stopped and the intensity of the color is measured.
Applications Used for the quantitative determination of Cusatuzumab concentration in serum and plasma.
Stability and Storage When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%.
Detection method Colorimetric
Precision CV<20%
Sample type Plasma, Serum
Assay type Quantitative
Sensitivity 85.26 ng/mL
Range 125 - 8,000 ng/mL
Recovery 80-120%
Background Cusatuzumab is designed as a first-in-class, high-affinity anti-CD70 monoclonal antibody with multiple intended mechanisms of action, including Fc-mediated cytotoxicity with enhanced ADCC and inhibition of CD70/CD27 signaling, resulting in killing of malignant cells such as leukemia blasts and stem cells.
Alternative Names ARGX-110, CAS: 1399546-01-0
Shipping 2-8 ℃
Note For Research Use Only.
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