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SKU(재고 관리 코드):KDJ04002
Mirzotamab ELISA Kit
Mirzotamab ELISA Kit
Catalog No.: KDJ04002
| Catalog No. | KDJ04002 |
|---|---|
| Product name | Mirzotamab ELISA Kit |
| Size | 96 T |
| Description | PRINCIPLE OF THE ASSAY This assay employs the quantitative competitive enzyme immunoassay technique. Recombinant Human CD276 has been pre-coated onto a microplate. Standards or samples are premixed with biotin-labeled antibody and then pipetted into the wells. Mirzotamab in the sample competitively binds to the pre-coated protein with biotin-labeled Mirzotamab. After washing away any unbound substances, Streptavidin-HRP is added to the wells. Following a wash to remove any unbound enzyme reagent, a substrate solution is added to the wells and color develops in inversely proportion to the amount of Mirzotamab bound in the initial step. The color development is stopped and the intensity of the color is measured. |
| Applications | Used for the quantitative determination of Mirzotamab concentration in serum and plasma. |
| Stability and Storage | When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. |
| Detection method | Colorimetric |
| Precision | CV<20% |
| Sample type | Plasma, Serum |
| Assay type | Quantitative |
| Sensitivity | 45.23 ng/mL |
| Range | 93.75 - 6,000 ng/mL |
| Recovery | 80-120% |
| Background | Mirzotamab clezutoclax (ABBV-155) is a first-in-class antibody drug conjugate comprised of a BCL-X L (B-cell lymphoma - extra long) inhibitor, solubilizing linker, and a monoclonal anti-B7H3 antibody. Methods: Patients (pts) with relapsed and/or refractory (R/R) solid tumors were administered mirzotamab clezutoclax with or without paclitaxel. Dose escalation of mirzotamab clezutoclax was guided by Bayesian continual reassessment. |
| Alternative Names | ABBV-155, CAS: 2229859-11-2 |
| Shipping | 2-8 ℃ |
| Note | For Research Use Only. |
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