APC Anti-Mouse CD14 Antibody[Sa14-2]

APC Anti-Mouse CD14 Antibody[Sa14-2]

APC Anti-Mouse CD14 Antibody [Sa14-2] is a highly specific monoclonal antibody that recognizes mouse CD14, a glycosylphosphatidylinositol-anchored protein expressed on the surface of monocytes, macrophages, and dendritic cells. This antibody is conjugated with APC (Allophycocyanin), a fluorescent dye that emits in the far-red region of the spectrum, making it ideal for flow cytometry and other fluorescence-based assays. The Sa14-2 clone has been extensively validated for its specificity and sensitivity, ensuring reliable and reproducible results.

This antibody is an essential tool for researchers studying the role of CD14 in innate immunity, inflammation, and infection. CD14 is a key receptor for lipopolysaccharide (LPS), a component of the outer membrane of Gram-negative bacteria, and other pathogen-associated molecular patterns (PAMPs). CD14 binding to LPS triggers a signaling cascade that leads to the production of pro-inflammatory cytokines and chemokines, as well as the activation of the adaptive immune response. APC Anti-Mouse CD14 Antibody [Sa14-2] can be used to detect CD14 expression on different cell types, to quantify CD14 levels in biological samples, and to investigate the functional consequences of CD14 activation.

In addition to its research applications, APC Anti-Mouse CD14 Antibody [Sa14-2] can also be used for diagnostic purposes. CD14 has been implicated in various diseases, such as sepsis, a life-threatening condition caused by a dysregulated immune response to infection. APC Anti-Mouse CD14 Antibody [Sa14-2] can be used to measure CD14 levels in patient samples, to monitor disease progression, and to evaluate the efficacy of therapeutic interventions. Overall, APC Anti-Mouse CD14 Antibody [Sa14-2] is a valuable reagent for anyone interested in studying or diagnosing CD14-related processes.