APC5 Polyclonal Antibody

ANAPC5 encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein (anaphase promoting complex subunit 5) is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

The APC5 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of APC5 protein in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, ensuring accurate and reproducible results.

The APC5 Polyclonal Antibody is produced using state-of-the-art techniques, guaranteeing high purity and batch-to-batch consistency. It has been rigorously tested for cross-reactivity with other proteins to ensure minimal interference and reliable performance.

This antibody is suitable for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It is compatible with various sample types, such as cell lysates, tissue extracts, and purified proteins.

The APC5 Polyclonal Antibody offers numerous advantages, including its versatility, robustness, and ease of use. It provides researchers with a valuable tool for studying the role of APC5 in cellular processes and disease mechanisms.

With its exceptional performance and reliability, the APC5 Polyclonal Antibody is an indispensable tool for scientists and researchers in the field of molecular biology, biochemistry, and cell biology.