APLP2 Polyclonal Antibody

APLP2 encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. Amyloid-like protein 2 is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in

the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

The APLP2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Amyloid Precursor-Like Protein 2 (APLP2) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human APLP2 protein. The APLP2 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody is suitable for use in both research and diagnostic applications. With its high specificity and sensitivity, the APLP2 Polyclonal Antibody is an essential tool for researchers and clinicians studying the role of APLP2 in various physiological and pathological processes.