ApoA-I Polyclonal Antibody

APOA1 encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein.

The ApoA-I Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of Apolipoprotein A-I (ApoA-I) in various biological samples. ApoA-I is a major component of high-density lipoprotein (HDL) particles and plays a crucial role in cholesterol metabolism and reverse cholesterol transport. This antibody is produced by immunizing animals with a synthetic peptide corresponding to a specific region of the ApoA-I protein sequence.

The ApoA-I Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate and precise measurement of ApoA-I levels in serum, plasma, and other biological fluids. It has been extensively validated and characterized to ensure consistent and reproducible results. This antibody demonstrates minimal cross-reactivity with other related proteins, ensuring reliable and specific detection of ApoA-I.

This high-quality antibody is suitable for various applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). It is supplied as a liquid formulation, ready for immediate use, and is compatible with standard laboratory protocols. The ApoA-I Polyclonal Antibody offers researchers a valuable tool for studying the role of ApoA-I in lipid metabolism, cardiovascular diseases, and other related fields.

With its exceptional performance and reliability, the ApoA-I Polyclonal Antibody is an indispensable asset for researchers and scientists seeking to explore the intricate mechanisms underlying lipid metabolism and its implications in various physiological and pathological conditions.