AR- Alpha1B Polyclonal Antibody

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells.

There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. ADRA1B encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. ADRA1B comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

The AR-Alpha1B Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using advanced techniques and is purified to ensure high quality and consistency. It is specifically designed to target the AR-Alpha1B protein, which is involved in a variety of cellular processes, including gene regulation and cell growth.

The AR-Alpha1B Polyclonal Antibody is suitable for use in a range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It is available in a range of sizes to suit different experimental needs. This antibody is an essential tool for researchers studying the AR-Alpha1B protein and its role in various biological processes. Its high specificity and sensitivity make it a reliable and effective tool for use in a wide range of research applications.