AR- Alpha2A Polyclonal Antibody

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. ADRA2A encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences.

The AR Alpha2A Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of the Alpha2A adrenergic receptor (AR) protein. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The AR Alpha2A Polyclonal Antibody exhibits excellent performance in detecting endogenous levels of the Alpha2A adrenergic receptor protein in a wide range of species, including human, mouse, and rat. It recognizes an epitope located within the N-terminal region of the AR protein, enabling accurate and precise identification of this crucial receptor.

With its high affinity and selectivity, this antibody offers researchers a valuable tool for investigating the role of the Alpha2A adrenergic receptor in various physiological and pathological processes. It allows for the exploration of receptor expression patterns, subcellular localization, and protein-protein interactions, facilitating a deeper understanding of the receptor's function and its involvement in disease mechanisms.

The AR Alpha2A Polyclonal Antibody is supplied as a liquid formulation, ensuring ease of use and convenience. It has been rigorously validated for its performance and quality, guaranteeing reliable and reproducible results. Each batch of antibody undergoes stringent quality control measures to ensure consistency and reliability, providing researchers with confidence in their experimental outcomes.

In summary, the AR Alpha2A Polyclonal Antibody is a highly specific and sensitive tool that enables accurate detection and analysis of the Alpha2A adrenergic receptor protein. Its exceptional performance and reliability make it an indispensable asset for researchers studying the role of this receptor in various biological processes and disease mechanisms.