AR-Beta2 Polyclonal Antibody

ADRB2 encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca (V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. ADRB2 is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

The AR-Beta2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of AR-Beta2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the human AR-Beta2 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The AR-Beta2 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting AR-Beta2 protein in various human tissues and cell lines. This antibody has been shown to recognize a single band of the expected molecular weight in Western blot analysis and to produce a strong and specific signal in immunohistochemistry and immunofluorescence assays.

This antibody is supplied as a liquid in phosphate-buffered saline (PBS) containing 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C or below for long-term storage and to avoid repeated freeze-thaw cycles.

In summary, the AR-Beta2 Polyclonal Antibody is a reliable and high-quality tool for the detection of AR-Beta2 protein in various biological samples. Its specificity and sensitivity make it an ideal choice for researchers studying the role of AR-Beta2 in various physiological and pathological processes.