AR-Beta2 Polyclonal Antibody

ADRB2 encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

The AR-Beta2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of AR-Beta2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the human AR-Beta2 protein. The AR-Beta2 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence applications.

The AR-Beta2 Polyclonal Antibody is a valuable tool for researchers studying the role of AR-Beta2 in various physiological and pathological processes. AR-Beta2 is a member of the androgen receptor (AR) family of transcription factors, which play critical roles in the development and progression of prostate cancer. AR-Beta2 has been shown to have distinct functions from the classical AR isoforms, and its expression has been implicated in the development of castration-resistant prostate cancer.

The AR-Beta2 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a protein A column. The antibody is provided in a liquid format, and it is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. The AR-Beta2 Polyclonal Antibody is available in different sizes to meet the needs of various research projects.

In summary, the AR-Beta2 Polyclonal Antibody is a highly specific and sensitive antibody that is ideal for the detection of AR-Beta2 protein in various biological samples. This antibody is a valuable tool for researchers studying the role of AR-Beta2 in prostate cancer and other physiological and pathological processes.