ARA54 Polyclonal Antibody

The protein encoded by RNF14 (ring finger protein 14) contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of RNF14 has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported.

The ARA54 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of ARA54 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the ARA54 protein.

The ARA54 Polyclonal Antibody exhibits exceptional affinity and selectivity towards ARA54, ensuring accurate and reliable results in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated and optimized to provide consistent and reproducible performance.

With its superior sensitivity, the ARA54 Polyclonal Antibody allows for the detection of low-abundance ARA54 protein levels, enabling researchers to study its expression patterns and functional roles in various biological processes. Its robust performance ensures minimal background noise and high signal-to-noise ratios, facilitating precise and reliable data interpretation.

The ARA54 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy customization and optimization of experimental conditions. Each batch of antibody undergoes rigorous quality control procedures to ensure batch-to-batch consistency and reliability.

In summary, the ARA54 Polyclonal Antibody is a valuable tool for researchers studying the ARA54 protein. Its exceptional sensitivity, specificity, and reliability make it an ideal choice for a wide range of applications, providing accurate and reproducible results.