ARF GAP3 Polyclonal Antibody

The ADP ribosylation factor GTPase activating protein 3 encoded by ARFGAP3 is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. ARFGAP3 was originally known as ARFGAP1, but that is now the name of a related but different gene.

The ARF GAP3 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of ARF GAP3 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques and exhibits exceptional sensitivity and specificity.

ARF GAP3, also known as ADP-ribosylation factor GTPase-activating protein 3, plays a crucial role in regulating intracellular vesicle trafficking and membrane dynamics. It functions as a GTPase-activating protein, catalyzing the hydrolysis of GTP bound to ADP-ribosylation factors (ARFs), thereby inactivating them. ARF GAP3 is involved in diverse cellular processes, including endocytosis, exocytosis, and vesicle formation.

The ARF GAP3 Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent specificity, showing minimal cross-reactivity with other related proteins. This antibody enables precise and accurate detection of ARF GAP3 protein expression, facilitating comprehensive studies on its cellular functions and molecular mechanisms.

With its high-quality formulation, the ARF GAP3 Polyclonal Antibody ensures consistent and reproducible results, making it an ideal choice for both basic research and clinical investigations. It is supplied in a convenient ready-to-use format, allowing for easy and efficient experimentation. Additionally, this antibody is produced in compliance with rigorous quality control standards, ensuring batch-to-batch consistency and reliability.

In summary, the ARF GAP3 Polyclonal Antibody is a valuable tool for researchers seeking to explore the intricate roles of ARF GAP3 in cellular processes. Its exceptional specificity, sensitivity, and reliability make it an indispensable asset in various experimental settings.