ARHGAP22 Polyclonal Antibody

ARHGAP22 (Rho GTPase activating protein 22) encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for ARHGAP22.

The ARHGEF16 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of ARHGEF16 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ARHGEF16 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity through various assays.

The ARHGEF16 Polyclonal Antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically detect ARHGEF16 protein in human, mouse, and rat tissues, making it a versatile tool for researchers studying the function and expression of this protein.

This antibody is supplied as a liquid solution in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C for long-term storage and to avoid repeated freeze-thaw cycles.

Overall, the ARHGEF16 Polyclonal Antibody is a reliable and high-quality tool for the detection of ARHGEF16 protein in various biological samples, making it an essential component of any research project focused on this protein.