ARHGEF9 Polyclonal Antibody

The Cdc42 guanine nucleotide exchange factor 9 encoded by ARHGEF9 is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.

The ARHGEF9 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of ARHGEF9 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity towards the target protein.

ARHGEF9, also known as collybistin, is a guanine nucleotide exchange factor that plays a crucial role in the regulation of neuronal development and synaptic function. It is primarily expressed in the brain and is involved in the formation and maintenance of inhibitory synapses. Dysregulation of ARHGEF9 has been implicated in various neurological disorders, making it an important target for research and diagnostic purposes.

The ARHGEF9 Polyclonal Antibody has been extensively validated for its specificity and performance in various experimental techniques, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, ready to use for immediate application. It is provided in a convenient size, allowing for multiple experiments without compromising its quality. The ARHGEF9 Polyclonal Antibody is manufactured under strict quality control standards, ensuring consistent and reproducible results.

In summary, the ARHGEF9 Polyclonal Antibody is a valuable tool for researchers and clinicians interested in studying the role of ARHGEF9 in neurological disorders. Its high specificity, sensitivity, and reliability make it an ideal choice for various experimental techniques, enabling accurate detection and analysis of ARHGEF9 protein expression.