ARP Polyclonal Antibody

Mesencephalic astrocyte-derived neurotrophic factor encoded by MANF is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.

The ARP Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of the target protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the target protein. The resulting polyclonal antibody is purified using a combination of protein A and protein G affinity chromatography to ensure high purity and specificity.

The ARP Polyclonal Antibody has been extensively validated for use in a wide range of applications, including Western blotting, immunohistochemistry, and ELISA. It has been shown to exhibit excellent sensitivity and specificity, with minimal cross-reactivity to other proteins. This antibody is suitable for use in both research and diagnostic applications.

The ARP Polyclonal Antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different applications. The antibody should be stored at -20°C or below and should not be subjected to repeated freeze-thaw cycles.

In summary, the ARP Polyclonal Antibody is a reliable and high-quality immunological reagent that offers excellent sensitivity and specificity for the detection and quantification of the target protein in various biological samples. Its versatility and ease of use make it an ideal choice for researchers and diagnostic laboratories alike.