ARRDC2 Polyclonal Antibody

ARRDC1, ARRDC2 (which exists as multiple alternatively spliced isoforms), ARRDC4 and ARRDC5 are arrestin domain-containing proteins that are encoded by genes which map to human chromosomes 9, 15 and 19. Chromosome 9, on which the ARRDC1 gene is localized, contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. The ARRDC2 and ARRDC5 genes map to chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. Unlike other ARRDC genes, the ARRDC4 gene maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

The ISG20 Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of ISG20 protein expression in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring exceptional sensitivity and specificity.

The ISG20 protein, also known as Interferon-stimulated exonuclease gene 20, plays a crucial role in the regulation of cellular antiviral responses. It is involved in the degradation of viral RNA and the inhibition of viral replication. The ISG20 Rabbit Polyclonal Antibody has been extensively validated for its ability to recognize endogenous levels of ISG20 protein in various cell lines and tissues.

This antibody exhibits excellent performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been optimized for use in both research and diagnostic settings, providing accurate and reproducible results.

The ISG20 Rabbit Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a 100 µg size, ensuring an ample amount for multiple experiments. The antibody is stored at -20°C, ensuring long-term stability and preserving its functionality.

In summary, the ISG20 Rabbit Polyclonal Antibody is a valuable tool for researchers and clinicians studying the role of ISG20 protein in antiviral responses. With its exceptional sensitivity, specificity, and versatility, this antibody enables accurate and reliable detection of ISG20 protein expression in various biological samples.