AT1 Polyclonal Antibody

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system.

It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. AGTR1 may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium.

It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.

The A-Raf Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of A-Raf protein in various biological samples.

This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human A-Raf protein. The A-Raf Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence applications.

This antibody is suitable for use in a wide range of research applications, including cancer research, signal transduction studies, and drug discovery. The A-Raf Polyclonal Antibody is supplied as a purified IgG fraction, and it is available in various sizes to meet the needs of different research projects. With its high specificity and sensitivity, the A-Raf Polyclonal Antibody is an essential tool for researchers studying A-Raf protein and its role in various biological processes.