ATF-2 Polyclonal Antibody

ATF2 encodes a transcription factor (activating transcription factor 2) that is a member of the leucine zipper family of DNA binding proteins. Activating transcription factor 2 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Activating transcription factor 2 binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Activating transcription factor 2 may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this ATF2.

The ARALAR Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of ARALAR protein in various biological samples. This antibody has been meticulously developed and rigorously validated to ensure optimal performance and reliability.

The ARALAR Polyclonal Antibody exhibits exceptional affinity and selectivity towards ARALAR, a key mitochondrial protein involved in the transport of aspartate and glutamate across the inner mitochondrial membrane. By targeting ARALAR, this antibody enables researchers to investigate the role of this protein in cellular metabolism, energy production, and neurotransmission.

This antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been extensively tested in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. The ARALAR Polyclonal Antibody consistently delivers robust and specific signals, allowing for accurate and reproducible results.

With its broad reactivity across multiple species, including human, mouse, and rat, the ARALAR Polyclonal Antibody is a versatile tool suitable for a wide range of research applications. Its exceptional sensitivity enables the detection of low abundance ARALAR protein, making it an invaluable asset for studies requiring precise quantification.

In summary, the ARALAR Polyclonal Antibody is a reliable and high-quality reagent that offers researchers a powerful tool for investigating the function and regulation of ARALAR protein. Its exceptional specificity, sensitivity, and versatility make it an indispensable asset in various fields, including biochemistry, cell biology, and neuroscience.