ATF-2 Polyclonal Antibody

ATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein (activating transcription factor 2) has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for ATF2.

The ISG20 Rabbit Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of ISG20 protein expression in various biological samples. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring exceptional sensitivity and specificity.

The ISG20 protein, also known as Interferon-stimulated exonuclease gene 20, plays a crucial role in the regulation of cellular antiviral responses. It is involved in the degradation of viral RNA and the inhibition of viral replication. The ISG20 Rabbit Polyclonal Antibody has been extensively validated for its ability to recognize endogenous levels of ISG20 protein in various cell lines and tissues.

This antibody exhibits excellent performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been optimized for use in both research and diagnostic settings, providing accurate and reproducible results.

The ISG20 Rabbit Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a 100 µg size, ensuring an ample amount for multiple experiments. The antibody is stored at -20°C, ensuring long-term stability and preserving its functionality.

In summary, the ISG20 Rabbit Polyclonal Antibody is a valuable tool for researchers and clinicians studying the role of ISG20 protein in antiviral responses. With its exceptional sensitivity, specificity, and versatility, this antibody enables accurate and reliable detection of ISG20 protein expression in various biological samples.