ATF-6Beta Polyclonal Antibody

The protein (activating transcription factor 6 beta) encoded by ATF6B is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for ATF6B.

Introducing the ATF-6Beta Polyclonal Antibody, a cutting-edge scientific tool designed to facilitate advanced research in the field of molecular biology. This high-quality antibody is meticulously developed using state-of-the-art techniques, ensuring exceptional specificity and sensitivity for the detection of ATF-6Beta protein.

The ATF-6Beta Polyclonal Antibody is derived from a diverse pool of immunized animals, resulting in a robust and reliable product. Its polyclonal nature allows for enhanced recognition of multiple epitopes, enabling comprehensive analysis of ATF-6Beta protein expression and localization in various biological samples.

With its exceptional affinity and selectivity, this antibody offers researchers an invaluable tool for investigating the intricate mechanisms underlying ATF-6Beta-mediated cellular processes. Whether studying endoplasmic reticulum stress response, unfolded protein response, or other related pathways, the ATF-6Beta Polyclonal Antibody provides unparalleled accuracy and reproducibility.

This antibody is rigorously validated through a series of stringent quality control measures, ensuring consistent performance across different experimental conditions. Its versatility allows for various applications, including Western blotting, immunohistochemistry, immunofluorescence, and immunoprecipitation, enabling researchers to explore ATF-6Beta protein dynamics in diverse experimental settings.

The ATF-6Beta Polyclonal Antibody is supplied in a convenient format, with different sizes available to suit individual research needs. Each vial is meticulously packaged to maintain optimal stability and integrity, guaranteeing long-term storage without compromising antibody performance.

In summary, the ATF-6Beta Polyclonal Antibody represents a cutting-edge scientific tool that empowers researchers to unravel the complexities of ATF-6Beta protein function. Its exceptional specificity, sensitivity, and versatility make it an indispensable asset for molecular biologists and scientists alike, facilitating groundbreaking discoveries in the field.