ATF-7 Polyclonal Antibody

Eukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis acting promoter and enhancer elements. The ATF/CREB transcription factor family binds the palindromic cAMP response element (CRE) octanucleotide TGACGTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB3 and Luman), CREM-1, CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. This family of proteins contain highly divergent N-terminal domains, but share a C-terminal leucine zipper for dimerization and DNA binding. ATF-5 (ATFx), which can localize to the cytoplasm or the nucleus, binds DNA as a dimer. It interacts with CCND3 and PTP4A1.

The ATF-7 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of ATF-7 protein expression in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and sensitivity.

ATF-7, also known as activating transcription factor 7, is a transcription factor that plays a crucial role in regulating gene expression and cellular processes. It is involved in diverse biological functions, including cell proliferation, differentiation, and apoptosis. The ATF-7 Polyclonal Antibody recognizes endogenous levels of ATF-7 protein, making it an ideal choice for studying its expression patterns and functional implications.

This antibody has been extensively validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional specificity, displaying minimal cross-reactivity with other related proteins. The ATF-7 Polyclonal Antibody demonstrates excellent performance in both human and animal samples, making it a versatile tool for researchers in various fields.

With its high sensitivity and specificity, the ATF-7 Polyclonal Antibody enables accurate and reliable detection of ATF-7 protein expression, facilitating in-depth investigations into its biological functions and regulatory mechanisms. Its superior performance and consistent results make it an indispensable tool for researchers aiming to unravel the complexities of ATF-7-mediated signaling pathways and its involvement in various physiological and pathological processes.

Order the ATF-7 Polyclonal Antibody today and unlock new insights into the intricate world of ATF-7 biology.