Atg4b Polyclonal Antibody

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

The Atg4b Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Atg4b protein expression in various biological samples. This antibody has been extensively validated for its exceptional performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications.

Atg4b, a member of the autophagy-related protein family, plays a crucial role in the regulation of autophagy, a cellular process involved in the degradation and recycling of cellular components. The precise detection and quantification of Atg4b protein expression are essential for understanding the intricate mechanisms underlying autophagy and its implications in various physiological and pathological conditions.

The Atg4b Polyclonal Antibody exhibits high affinity and specificity towards Atg4b protein, ensuring accurate and reproducible results. It has been rigorously tested and validated using a wide range of cell lines and tissue samples, guaranteeing its reliability and consistency across different experimental setups.

This antibody offers exceptional sensitivity, enabling the detection of even low levels of Atg4b protein expression. Its robust performance in IHC allows for precise localization and visualization of Atg4b within tissues, facilitating detailed cellular and subcellular analysis. Additionally, its compatibility with IF enables co-localization studies, providing valuable insights into the spatial distribution and interaction of Atg4b with other cellular components.

Furthermore, the Atg4b Polyclonal Antibody demonstrates excellent performance in WB, enabling the detection and quantification of Atg4b protein in cell lysates. Its high specificity ensures minimal cross-reactivity with other proteins, enhancing the accuracy and reliability of the obtained results.

In summary, the Atg4b Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of Atg4b protein expression. Its exceptional performance in IHC, IF, and WB applications, coupled with its sensitivity and specificity, make it an invaluable asset for researchers studying autophagy and its implications in various biological processes and diseases.